Different types of Vitamin B12:
Which one is tight for you?

Struggling to find your way through the maze of supplements and vitamins? You’re not alone. In the search for optimal health, vitamin B12 stands out as a critical nutrient, essential for everything from brain function to energy levels.

But here’s the catch: not all vitamin B12 is created equal. With various forms like Cyanocobalamin and Methylcobalamin, each offers unique benefits, and choosing the right one can be the difference between feeling just okay and feeling your absolute best.

Delve into the diverse world of vitamin B12 types with this article, empowering you to make informed choices.

Whether battling fatigue, pursuing mental clarity, or striving for peak wellness, understanding these variants can be your game-changer.

What are the four types of vitamin B12?

Vitamin B12, essential for various bodily functions like nerve function and red blood cell formation, comes in four primary types. Each type has its unique properties and benefits.


Methylcobalamin is the most active form of Vitamin B12 in the human body. It plays a crucial role in converting homocysteine into methionine to aid cardiovascular protection. Moreover, it’s vital for nervous system health and can cross the blood-brain barrier without assistance to offer protection to brain cells.


Cyanocobalamin, a synthetic version of Vitamin B12, is the most stable but contains a cyanide molecule. Although the cyanide amount is not harmful, the body expends energy to remove it. This form is often the cheapest supplement option.


Hydroxocobalamin is naturally created by bacteria and is the main type found in most foods. In the human body, it easily converts into Methylcobalamin. It’s frequently used in injections for treating B12 deficiency and cyanide poisoning.


Adenosylcobalamin is vital for the Citric Acid Cycle, a key energy formation process in the body. Though naturally occurring, it is the least stable outside the human body. This makes it rare in tablet-based supplements.

Methylcobalamin vs Cyanocobalamin

When comparing Methylcobalamin and Cyanocobalamin, the former is more active and directly usable in the body by supporting the nervous system and detoxification. Cyanocobalamin, while more stable and affordable, requires the body to convert it into a usable form which involves the removal of a cyanide molecule.

How to treat vitamin B12 deficiency

Vitamin B12 deficiency can lead to several health issues, including fatigue, memory loss, and nerve damage. The treatment involves increasing intake through diet or supplements.

Vitamin B12 foods include dairy products, eggs, fortified cereals, salmon, tuna, beef, liver, and clams. For those unable to absorb B12 from food due to lack of stomach acid or other conditions, supplements are recommended.

The recommended daily Vitamin B12 dosage for adults is 2.4 micrograms, but higher doses are considered safe as the body absorbs only what it needs.

Unlock your health potential

In your journey to wellness, the right type of vitamin B12 can be a pivotal ally. At Body Rejuvenation, we understand the unique needs of every individual and offer personalized solutions that align with your wellness goals.

Good health isn’t a one-size-fits-all scenario. It’s about finding what works for you, and we’re here to guide you on that path.

Eager to learn more and transform your well-being? Sign up for our newsletter for cutting-edge insights on longevity and anti-aging, and snag a sweet 10% discount on your journey to a revitalized you.

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Luis Martinez

Dr. Luis Martínez is a Regenerative Medicine, Antiaging and Cell Therapy specialist, clinical researcher and biomedical consultant. He earned his medical degree at The Ponce School of Medicine and completed his residency training at the prestigious University of Pennsylvania. Dr. Martinez is also CoFounder of the Clinical Peptide Society, a US based professional organization aimed at educating physicians and advancing the use of peptide therapeutics.

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